skip to Main Content

Zoe Harcombe: PCSK9 Inhibitors do not show clinical end benefits

http://www.DoctorsToTrust.com
presents episode 273: Dr Zoe Harcombe
at
Low Carb All Stars
June 2021
www.zoeharcombe.com/LCAS21

PCSK9 inhibitor medications
-block the enzyme PCSK9, which
-blocks LDL from being removed from the blood
-the result: lowered LDL levels

2017 clinical trial of drug, Evolocumab (PCSK9 inhibitor)…
-2 groups: intervention group & placebo group
-intervention group had their cholesterol lowered
-placebo group’s cholesterol is higher

Key point:
these drugs do lower
cholesterol, but:
is this a clinical benefit?

2017 clinical trial of drug, Evolocumab (PCSK9 inhibitor)…
-results:
-placebo group coronary revascularizations were 27% higher
-easy to recommend them by doctors concerned about LDL
-this subjective part
has large influence on
total study data

To access her citations:
Go to her website: www.zoeharcombe.com/LCAS21.
Here find a list of all the slides from her presentation.
Each slide has the title and the reference for the study she cites with its link.