PAUL MASON 2a | High triglycerides; low HDL: risk factors for BLOOD CLOTS
presents episode 673 | Dr Paul Mason
Low Carb Down Under podcast
Within atherosclerotic plaques are blood clots:
-platelets [play key role initiating blood clotting] -fibrin [fibrous strands binds it all together]
Study: removed sections of plaque…
-found evidence of all these ingredients
-found proof of red blood cells DEEP WITHIN PLAQUE
New England Journal of Medicine…
-clearly describes central
accumulation of red blood
membrane within the plaques
Animals, injected with blood,
produced plaques having both
blood clots central to development of atherosclerosis
“Clotting risk must also be risk for atherosclerosis
Question: Do lipids have anything to do with clotting?
High triglycerides & low HDL are risk factors for heart disease
Question: do these metrics have any association with clotting?
Dozens of papers show connection of lipids and clotting
Low HDL removes the break on clot formation
Oxidized LDL [small, dense] promotes platelet clumping &
-tissue factor–stimulates clotting
Key: What we consider lipid risk factors are actually:
clotting risk factors
low HDL: independent risk factors for clotting
Original Youtube: https://youtu.be/-xCr3mvFCHM
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