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NADIR ALI f’ | AMYLOID PROTEIN in brain SHUTS DOWN in insulin resistance
presents episode 1079 | Dr Nadir Ali
Nadir Ali MD podcast

Membrane proteins in brain…
AMYLOID protein involved in neuron
-attracts white blood cells so brain can
protect itself from infection
Amyloid Beta is breakdown product
of amyloid precursor protein
Works well when insulin sensitive
In insulin resistance: does not work

ApoE4:: designed to eat ancestral diet
More at risk of insulin resistance with modern diet
Higher LDL
Higher heart disease
Higher risk Alzheimers
Should: intermittent fast, be physical
Statins make insulin resistance WORSE

ApoE4: Must recover & repair insulin receptors…
-restore insulin-glucagon interaction
ApoE4 best for this because
-no meds can help
1-intermittent fasting
2-severely restrict carbs


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