skip to Main Content

NADIR ALI b’ | Injected insulin can’t match natural insulin: glucagon response: bad glucose control
presents episode 1075 | Dr Nadir Ali
Nadir Ali MD podcast

Pancreas: red cells are insulin-producing beta cells…
-green produce glucagon
Type 1 diabetics have no
beta cells
Type 2 diabetics have
hypertrophied beta cells
[ineffective] Both alpha & beta cells
close to each other…
Dr Unger asked: is this
for a purpose?

Paracrine signaling: means local control
[endocrine means signal comes from pancreas] -insulin created in pancreas
to have effect on brain
Insulin begins in beta cells
-highest concentration at
alpha cells making
“Role of insulin is to SHUT
[from Dr Roger Unger]

From Dr Roger Unger:
When insulin reaches liver, it is diluted 10x…
-when enters circulation:
diluted 100x
Injected insulin can
[liver will never see this
normal concentration of

From Dr Roger Unger:
As there are slight fluctuations in sugar
-beta cells release insulin
in phase 1 response
-in a squirt to suppress
Continues to suppress
glucagon thru phase 2

When not eating, glucagon levels are high…
Tells liver: put out sugar
-burn muscles, convert to
-take glycerol from fat &
convert to sugar
-take fatty acids &
convert to KETONES

Paracrine action between alpha and beta cells when eating…
-insulin tells :
-use & store sugar
-build new protein
-store fat
glucagon tells:
-release sugar from liver
-break down protein to
make sugar
-release fat for sugar & ketones


Original Youtube:
This site will never use corruptible, epidemiological survey research as causal science.
For each short/sharable video, the original Youtube links are provided

None of this content is intended to be individual, personalized medical advice.

We hope you find value for yourself in these short videos &
find them easy to share with loved ones!

The DoctorsToTrust videos are for general informational purposes only
and do not constitute the practice of medicine, nursing or other
professional health care services, including the giving of medical advice,
and no doctor/patient relationship is formed. The use of information on this podcast
or materials linked from this podcast is at the user’s own risk.
The content of this podcast is not intended to be a substitute for
professional medical advice, diagnosis, or treatment. Users should not disregard or
delay in obtaining medical advice for any medical condition they may have and
should seek the assistance of their health care professionals for any such conditions.

This Post Has 0 Comments

Leave a Reply

Your email address will not be published. Required fields are marked *