BEN BIKMAN f’ | CHRONIC STRESS at WAR with insulin! CORTISOL drives insulin resistance
presents episode 1028 | Dr Ben Bikman
Dr Steven Lin podcast
3 main drivers of insulin resistance…
-stress [cortisol & epinephrine] shown in research in
-isolated cells; rodents; humans
CORTISOL & EPINEPHRINE directly
cause insulin resistance
both want to push glucose UP
Cortisol will strip protein from muscles & bones
in order to turn it into glucose
-at odds with insulin
[driving glucose down] WAR between stress hormones & insulin
In clinic: if one given cortisol-like steroid
to control inflammation: will become
very insulin resistant very quickly
Question: acute stress? affect on insulin resistance…
-rapidly onset and rapidly gone
Sleep deprivation causes stress
-brings on insulin resistance, but
-one good night sleep relieves it
“Acute stress-driven insulin resistance:
rapid on and rapid off”
Original Youtube: https://www.youtube.com/live/w0DJNsLB5sw?feature=share
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